Signs & Symptoms
As Louping-ill belongs to the TBE group of Flaviviridae, the course of the disease, symptoms, and treatment is much the same as with TBE. It varies only in the intensity of viremia. The virus initially replicates in lymphoid tissue. Overt clinical signs are usually absent until the virus enters the central nervous system. Symptoms of neurological dysfunction can be to varying degrees, including severe encephalomyelitis.
The severity of clinical disease can be markedly increased if the host has a concurrent infection with Anaplasmosis or Borreliosis.